A new vesicular compartment in Encephalitozoon cuniculi

A new vesicular compartment in Encephalitozoon cuniculi.

The microsporidia are emerging human and veterinary pathogens known to infect every tissue type and organ system. Their infectious spore possesses a number of peculiar organelles, including the diagnostic polar tube. In a proteomics-driven effort to find novel components of this organelle in the human-pathogenic species Encephalitozoon cuniculi, we unexpectedly discovered a protein which locali...

Encephalitozoon cuniculi Infection in Rabbits

intracellular parasite in the phylum Microspora, which is defined by its resistant spore stage. Microsporidia receive little attention in veterinary medical curricula because they are considered important only as parasites of rabbits and fish. Microsporidia are important parasites of humans as well, with some species causing severe disease and death in immunocompromised individuals. Microsporid...

Identification of a new spore wall protein from Encephalitozoon cuniculi.

Microsporidia form environmentally resistant spores that are critical for their host-to-host transmission and persistence in the environment. The spore walls of these organisms are composed of two layers, the exospore and the endospore. Two spore wall proteins (SWP1 and SWP2) have been previously identified in members of the Encephalitozoonidae family. These proteins localize to the exospore. T...

Immune Response Against Encephalitozoon cuniculi Infection

Encephalitozoon Cuniculi as a Kidney Parasite in the Rabbit

A spontaneous epidemic of nephritis among young rabbits associated with a protozoan parasite has been observed in a certain breeding stock since 1918. It is regarded as a nest infection. The parasite is tentatively classed among the microsporidia and the stages encountered are regarded as vegetative which may perhaps pass through several generations in the same host. It is a parasite of the epi...